The tendency to identify new business opportunities is in their genes. Income from self-employment is heritable, which means that genetics affect not only the tendency to participate in entrepreneurship, but also the ability to do it. There are genetic factors that make some people more likely to be entrepreneurs than others. Genetic variants that are related to entrepreneurship make people who have them more likely to take risks and be self-employed.
These genes are linked to the receptors for the neurotransmitters dopamine and serotonin. However, the environment plays an important role in professional and life choices. Despite several attempts in the last decade, until now, no strong association has been discovered between genetic variants and entrepreneurship. Our overview and analysis of these papers give a clear answer to our first research question: “Why has the identification of strong associations between genetic variants and entrepreneurship not been successful in the last decade? Regardless of whether a hypothesis-based or hypothesis-free approach was used, until now genetic discovery studies on entrepreneurship have not had enough power.
However, based on the results of large-scale genetic discovery studies on other behavioral traits (such as educational attainment), we can expect strong associations between genetic variants and entrepreneurship to be identified if a sufficiently large sample can be gathered. Datasets containing both genetic data and entrepreneurship information are relatively scarce (Van der Loos et al. Therefore, a sufficiently powerful entrepreneurship GWAS could soon be feasible. He took over the family business with his two brothers in 1968, told his seven children not to set their sights on joining the then second-generation furniture company.
Due to large-scale collections of genetic data and experience on the biological functioning of genes in the fields of medicine and biology, the involvement of researchers in these fields will remain crucial in finding associations between genetic variants and entrepreneurship. Studies analyzing the heritability of entrepreneurship indicate that explanations for why people participate in gene-ignoring ventures are incomplete. For example, previous research shows that body height is associated with entrepreneurship (Rietveld et al. Due to data constraints, the latest and largest GWAS on entrepreneurship used self-employment as an indicator of entrepreneurship (Van der Loos et al.
Self-employment is the most commonly used measure for entrepreneurship studies based on survey data (Parker 201), although participation in self-employment can be episodic. There are advances in the collection of genetic data in economic-focused surveys (such as the US Health and Retirement Study and the English Longitudinal Study of Ageing), but at this time there is no analysis sample large enough for a GWAS on entrepreneurship. In summary, although attempts to identify specific genetic variants underlying heritable variation in entrepreneurship have so far been unsuccessful, there is reason to rely on the eventual success of the “business gene search” (Van der Loos et al. In short, genes matter, but they definitely don't determine entrepreneurship, or any behavioral outcome.
In addition, this study found no evidence that any of the genes previously suggested in the literature to influence entrepreneurship (Shane 20) show significant associations with entrepreneurship. However, this percentage will increase if the GWAS for the enterprise increases in terms of sample size (Dudbridge 201). An advantage of this approach is that genetic effects in closer outcomes are likely to be stronger and therefore easier to detect, for a given sample size, than genetic effects in distal results, such as entrepreneurship (Rietveld et al. Entrepreneurship is a complex phenotype, and it is highly unlikely that there is a strong association between having a variant of a particular gene and the tendency to participate in entrepreneurship.
Fortunately, for idealists like me, current research suggests that the role of genetics in the probability and success of entrepreneurship is not too strong. . .